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If you heard the phrases “K2,” “Spice,” “Kush,” or “synthetic marijuana,” would you know what that meant?

“Synthetic marijuana, also marketed under brand names like Spice and K2, is actually a broad category of synthetic cannabinoids produced in laboratories that attempt to mimic THC, the psychoactive compound in marijuana,” according to Vox News. “Synthetic cannabinoids are often marketed as ‘legal highs,’ but the federal government classified most of the chemicals used to produce them as schedule 1 substances, making it illegal to buy, sell, or possess anything containing the chemicals, even though it’s still sold in some stores around the country.”

Sellers will often try to get around the legality by labeling the packages “Not for human consumption.” But users know to look past that label.

Even the original creator of the chemical is on record about how dangerous the substance is.

“One of the original chemists who designed synthetic cannabis for research purposes, John Huffman, once said that he couldn’t imagine why anyone would try it recreationally,” according to an article in Forbes. “Because of its deadly toxicity, he likened it to playing Russian roulette.”

According to the National Institute on Drug Abuse, some of the effects include altered awareness of surrounding objects and conditions, symptoms of psychosis (delusional or disordered thinking detached from reality), extreme anxiety, confusion, paranoia, hallucinations, rapid heart rate, vomiting, seizures, violent behavior, strokes, or suicidal thoughts.

Since these products are illegal, they’re not regulated for consistency, and effects on each person can vary greatly. Here’s a documentary from our friends at the Bay Area Council on Drugs and Alcohol with interviews from people with personal experience with the substance.

One example is Emily Bauer story. Emily was 16 when she smoked synthetic marijuana from the same pack as her boyfriend. He didn’t suffer any ill effects. She had several strokes and is still recovering the mental and physical abilities she lost. Read more about her story here.

The harmful effects from these products were first reported in the U.S. to Poison Control in 2009. Poison centers received 2,668 calls about exposures to these drugs in 2013, 3,682 exposures in 2014, and 7,794 exposures in 2015. Last month alone poison centers received reports of 135 exposures to synthetic cannabinoids.

Even though the substance has been abused for years, researchers only began testing the effects more recently. In November, researchers in the Netherlands and Germany administered doses of a serum derived from JWH-018, a type of synthetic marijuana, to participants and observed the effects.

“They found that even a low dose (2 mg) impaired the users’ behavior,” reads the article on the study in Newsweek. “Users and bystanders often report the synthetic version as more incapacitating, even rendering people ‘zombielike.’ The rise in overdoses across the country from users who didn’t know what they were in for would seem to support this.”

It’s important that parents talk to their kids about the dangers of this fairly new drug. Time after time, teens report that their parents’ approval is the No. 1 deciding factor in their choice to use substances. Make sure your teen knows the dangers of synthetic marijuana and that you outline consequences for them that are appropriate for your family.